Our research activities continue in full compliance with the indications provided by the health authorities

The Neurophysiology Lab is based at the IRCCS San Giovanni di Dio Fatebenefratelli Center in Brescia, a national center of excellence in rehabilitation for psychiatric disorders and for Alzheimer’s disease.
Our research unit investigates neural mechanisms underlying behavior and cognitive processes in normal and pathological conditions. We have considerable experience in the field of neurophysiology: in the last 15 years, we have been employing non-invasive brain stimulation techniques, like transcranial magnetic stimulation (TMS) and transcranial electrical stimulation (tES), also combined with other electrophysiological methods (Electroencephalography – EEG).
The main goal of the activities carried out at the Cognitive Neuroscience Section is to improve the understanding of brain functioning and to translate the new findings obtained in the laboratory into clinical practice. In particular… (continues)



M. Pievani, A. Mega, G. Quattrini, G. Guidali, C. Ferrari, A. Cattaneo, I. D’Aprile, L. Mascaro, R. Gasparotti, D. Corbo, D. Brignani, M. Bortoletto (2021). Targeting Default Mode Network dysfunction in persons at risk of Alzheimer’s Disease with Transcranial Magnetic Stimulation (NEST4AD): Rationale and Study Design. Journal of Alzheimer’s Disease, doi: 10.3233/JAD-210659
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A. Zazio, C. Miniussi, M. Bortoletto (2021). Alpha-band cortico-cortical phase synchronization is associated with effective connectivity in the motor network. Clinical Neurophysiology, doi: 10.1016/j.clinph.2021.06.025
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M. Esposito, C. Ferrari, C. Fracassi, C. Miniussi, D. Brignani. Arousal levels explain inter-subject variability of neuromodulation effects. BioRxiv, doi: 10.1101/2020.05.08.083717
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